Heterochromatin density (condensation) during cell differentiation and maturation using the human granulocytic lineage of chronic myeloid leukaemia as a convenient model
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F11%3A00009336" target="_blank" >RIV/00023736:_____/11:00009336 - isvavai.cz</a>
Result on the web
<a href="http://fb.cuni.cz/file/5602/FB2011A0031.pdf" target="_blank" >http://fb.cuni.cz/file/5602/FB2011A0031.pdf</a>
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Heterochromatin density (condensation) during cell differentiation and maturation using the human granulocytic lineage of chronic myeloid leukaemia as a convenient model
Original language description
The granulocyte lineage in the bone marrow of patients suffering from chronic myeloid leukemia represents a convenient model for DNA image measurements in single cells because of their large number in all developmental stages. In addition the morphologyof these cells is similar to that of non-leukemic ones. The differentiation and maturation of granulocytes is accompanied by an increasing heterochromatin condensation in the peripheral regions of the cell nucleus. Thus, the peripheral chromosomal territories apparently participate in these events. The persistence of a low heterochromatin condensation might represent a further type of the maturation asynchrony of the leukemia cell, From the methodological point of view the used cytochemical method for the DNA demonstration and the panoptic May-Grünwald-Giemsa staining are convenient for computer assisted chromatin densitometry at the single cell level.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—
Result continuities
Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Folia Biologica
ISSN
0015-5500
e-ISSN
—
Volume of the periodical
57
Issue of the periodical within the volume
5
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
216-221
UT code for WoS article
000297182800006
EID of the result in the Scopus database
—