The DNA chromatin condensation expressed by the image optical density of chromosomes and chromatin in proliferating single human leukemic granulocytic progenitors
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F12%3A00010472" target="_blank" >RIV/00023736:_____/12:00010472 - isvavai.cz</a>
Result on the web
<a href="http://www.zsf.jcu.cz/jab/10_2/smetana.html" target="_blank" >http://www.zsf.jcu.cz/jab/10_2/smetana.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/v10136-011-0005-4" target="_blank" >10.2478/v10136-011-0005-4</a>
Alternative languages
Result language
angličtina
Original language name
The DNA chromatin condensation expressed by the image optical density of chromosomes and chromatin in proliferating single human leukemic granulocytic progenitors
Original language description
As it is generally known, the heterochromatin is an useful marker of the cell maturity including its pathology. The goal of the study was to provide more information on the heterochromatin DNA state in chromosomes and central gene rich nuclear regions ofsingle proliferating progenitors of human leukemic granulocytes. The computer image densitometry at the single cell level indicated that heterochromatin fibrils of similar width in the central nuclear regions are characterized by a similar DNA heterochromatin condensation state. Thus the DNA segments in heterochromatin fibrils represent masked chromosomal segments, which possibly carry silent genes. This observation is in harmony with the ?classical cytology? according to which such chromatin regions correspond to the chromosomal territories.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of applied biomedicine
ISSN
1214-021X
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
103-108
UT code for WoS article
000300929300005
EID of the result in the Scopus database
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