Deletion of the long arm but not the 5q31 region of chromosome 5 in myeloid malignancies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F12%3A00009362" target="_blank" >RIV/00023736:_____/12:00009362 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/12:12176 RIV/00064165:_____/12:12176
Result on the web
<a href="http://dx.doi.org/10.1016/j.leukres.2011.11.007" target="_blank" >http://dx.doi.org/10.1016/j.leukres.2011.11.007</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.leukres.2011.11.007" target="_blank" >10.1016/j.leukres.2011.11.007</a>
Alternative languages
Result language
angličtina
Original language name
Deletion of the long arm but not the 5q31 region of chromosome 5 in myeloid malignancies
Original language description
Deletion of the long arm of chromosome 5 is a recurrent cytogenetic abnormality that is frequently found in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). The proximal commonly deleted region CDR in the 5q31.2 region has been detectedin MDS, AML and therapy-related MDS/AML. The distal CDR in the 5q32-q33 region is involved in the pathogenesis of 5q- syndrome. Using molecular cytogenetic techniques, we identified an atypical 5q deletion with retained CDRs in three patients with myeloid diseases. To our knowledge, this is the first report describing 5q14-q23 deletions as the only abnormalities in MDS/AML patients.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Leukemia Research
ISSN
0145-2126
e-ISSN
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Volume of the periodical
36
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
3
Pages from-to
"e43"-"e45"
UT code for WoS article
000299316700001
EID of the result in the Scopus database
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