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Frequent alterations in messenger RNA splicing in myelodysplastic syndromes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F18%3A00011943" target="_blank" >RIV/00023736:_____/18:00011943 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.novapublishers.com/catalog/product_info.php?products_id=63968" target="_blank" >https://www.novapublishers.com/catalog/product_info.php?products_id=63968</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Frequent alterations in messenger RNA splicing in myelodysplastic syndromes

  • Original language description

    Author discusses splicing of pre-mRNAs coding for proteins. Since the discovery of frequent spliceosomal gene mutations which occur in about 65% of patients with myelodysplastic syndrome (MDS), we know that splicing factor gene mutations are the most frequent mutations found in MDS patients. Predominantly, four splicing factor genes (SF3B1, SRSF2, U2AF1, ZRSR2) are mutated in MDS and related malignancies.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    mRNA: molecular biology, processing and function

  • ISBN

    978-1-53613-168-0

  • Number of pages of the result

    25

  • Pages from-to

    97-122

  • Number of pages of the book

    152

  • Publisher name

    Nova Science

  • Place of publication

    New York

  • UT code for WoS chapter