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Two subpopulations of progenitors of leukemic lineages in human myeloid leukemias exhibit different heterochromatin condensation state in central and peripheral nuclear regions (A morphological note with additional original observations)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F20%3A00013138" target="_blank" >RIV/00023736:_____/20:00013138 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.15761/ICST.1000343" target="_blank" >https://doi.org/10.15761/ICST.1000343</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.15761/ICST.1000343" target="_blank" >10.15761/ICST.1000343</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Two subpopulations of progenitors of leukemic lineages in human myeloid leukemias exhibit different heterochromatin condensation state in central and peripheral nuclear regions (A morphological note with additional original observations)

  • Original language description

    The computer assisted optical image densitometry indicated that myeloid leukemias were characterized by two subpopulations of progenitor cells classified according to the heterochromatin condensation state (HChCS). The first subpopulation of these cells was characterized by a larger HChCS in the nuclear central regions than in the nuclear periphery. Such progenitors seemed to possess the potential for further differentiation and were predominantly present in patients suffering from the chronic phase of chronic myelocytic and acute monoblastic leukemias. The second subpopulation of progenitors was characterized by a marked similarity of HChCS in both central and peripheral nuclear regions. That similarity was also noted in terminally differentiated granulocytes and monocytes.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>ost</sub> - Miscellaneous article in a specialist periodical

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Integrative cancer science and therapeutics

  • ISSN

    2056-4546

  • e-ISSN

  • Volume of the periodical

    7

  • Issue of the periodical within the volume

    [August]

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    3

  • Pages from-to

    1-3

  • UT code for WoS article

  • EID of the result in the Scopus database