The mini-mental state examination: Czech norms and cutoffs for mild dementia and mild cognitive impairment due to Alzheimer's disease

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F16%3A43915149" target="_blank" >RIV/00023752:_____/16:43915149 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/16:43912197 RIV/00064173:_____/16:N0000103
Result on the web
<a href="http://www.karger.com/Article/FullText/446426" target="_blank" >http://www.karger.com/Article/FullText/446426</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000446426" target="_blank" >10.1159/000446426</a>

Result language
angličtina
Original language name
The mini-mental state examination: Czech norms and cutoffs for mild dementia and mild cognitive impairment due to Alzheimer's disease
Original language description
Background: There is a lack of normative studies of the Mini-Mental State Examination (MMSE) for comparison with early Alzheimer's disease (AD) according to new diagnostic criteria. Participants and Methods: We administered the MMSE to normal elderly Czechs and to patients with mild cognitive impairment (MCI) and mild dementia due to AD according to NIA-AA criteria. Results: We established percentile- and standard deviation-based norms for the MMSE from 650 normal seniors (age 69 +- 8 years, education 14 +- 3 years, MMSE score 28 +- 2 points) stratified by education and age. Dementia patients scored significantly lower than the MCI patients and both groups (110 early AD patients) had significantly lower MMSE scores than the normal seniors (22 +- 5 or 25 +- 3 vs. 28 +- 2 points) (p < 0.01). The optimal cutoff was LESS-THAN OR EQUAL TO27 points with sensitivity of 86% and specificity of 79% for early detection of AD patients. Conclusion: We provided MMSE norms, several cutoffs, and higher cutoff scores for early AD using recent guidelines.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/NT13183" target="_blank" >NT13183: Brief psychometric instruments for early diagnosis of Alzheimer's disease in senior population</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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