Validation of the Czech montreal cognitive assessment for mild cognitive impairment due to Alzheimer disease and Czech norms in 1,552 elderly persons

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F18%3A43919699" target="_blank" >RIV/00023752:_____/18:43919699 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/18:43917368 RIV/00064173:_____/18:N0000182

Result on the web

<a href="https://www.karger.com/Article/FullText/494489" target="_blank" >https://www.karger.com/Article/FullText/494489</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000494489" target="_blank" >10.1159/000494489</a>

Result language

angličtina

Original language name

Validation of the Czech montreal cognitive assessment for mild cognitive impairment due to Alzheimer disease and Czech norms in 1,552 elderly persons

Original language description

Background: The Czech version of the Montreal Cognitive Assessment (MoCA-CZ) and delayed recall of 5 words have not been validated in patients with mild cognitive impairment (MCI) due to Alzheimer disease (AD) and compared to norms of a large population. Method: The MoCA-CZ was administered to 1,600 elderly individuals in 2 groups consisting of 48 patients with MCI due to AD (AD-MCI) and 1,552 normal elderly adults. Results: MoCA-CZ scores were significantly lower in the AD-MCI patients than in the normal elderly (21 ± 4 vs. 26 ± 3 points; p = 0.03). Under the recommended cutoff score of ≤25, the MoCA-CZ demonstrated an excellent sensitivity of 94% but a low specificity of 62%. When the score was reduced to ≤24, the MoCA-CZ showed an optimal sensitivity of 87% for AD-MCI and a specificity of 72%. Normal elderly persons should recall at least 2 words after delay (sensitivity 80%, specificity 74%). Several cutoff points were derived from normative data stratified by age and education. Conclusions: The cutoff for AD-MCI and stratified norms are available for the MoCA total score and delayed recall of the Czech version. The cut-off scores of the MoCA-CZ, sensitivity, and specificity are lower than in the original study.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30210 - Clinical neurology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Dementia and Geriatric Cognitive Disorders

ISSN

1420-8008

e-ISSN

—

Volume of the periodical

46

Issue of the periodical within the volume

5-6

Country of publishing house

CH - SWITZERLAND

Number of pages

11

Pages from-to

335-345

UT code for WoS article

000456155700009

EID of the result in the Scopus database

—