Validation of the Czech Montreal Cognitive Assessment for Mild Cognitive Impairment due to Alzheimer Disease and Czech Norms in 1,552 Elderly Persons
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F18%3AN0000182" target="_blank" >RIV/00064173:_____/18:N0000182 - isvavai.cz</a>
Alternative codes found
RIV/00023752:_____/18:43919699 RIV/00216208:11120/18:43917368
Result on the web
<a href="https://doi.org/10.1159/000494489" target="_blank" >https://doi.org/10.1159/000494489</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000494489" target="_blank" >10.1159/000494489</a>
Alternative languages
Result language
angličtina
Original language name
Validation of the Czech Montreal Cognitive Assessment for Mild Cognitive Impairment due to Alzheimer Disease and Czech Norms in 1,552 Elderly Persons
Original language description
BACKGROUND: The Czech version of the Montreal Cognitive Assessment (MoCA-CZ) and delayed recall of 5 words have not been validated in patients with mild cognitive impairment (MCI) due to Alzheimer disease (AD) and compared to norms of a large population. METHOD: The MoCA-CZ was administered to 1,600 elderly individuals in 2 groups consisting of 48 patients with MCI due to AD (AD-MCI) and 1,552 normal elderly adults. RESULTS: MoCA-CZ scores were significantly lower in the AD-MCI patients than in the normal elderly (21 +- 4 vs. 26 +- 3 points; p = 0.03). Under the recommended cutoff score of LESS-THAN OR EQUAL TO25, the MoCA-CZ demonstrated an excellent sensitivity of 94% but a low specificity of 62%. When the score was reduced to LESS-THAN OR EQUAL TO24, the MoCA-CZ showed an optimal sensitivity of 87% for AD-MCI and a specificity of 72%. Normal elderly persons should recall at least 2 words after delay (sensitivity 80%, specificity 74%). Several cutoff points were derived from normative data stratified by age and education. CONCLUSIONS: The cutoff for AD-MCI and stratified norms are available for the MoCA total score and delayed recall of the Czech version. The cut-off scores of the MoCA-CZ, sensitivity, and specificity are lower than in the original study.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30210 - Clinical neurology
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Dementia and Geriatric Cognitive Disorders
ISSN
1420-8008
e-ISSN
1421-9824
Volume of the periodical
46
Issue of the periodical within the volume
5-6
Country of publishing house
CH - SWITZERLAND
Number of pages
11
Pages from-to
335-345
UT code for WoS article
000456155700009
EID of the result in the Scopus database
2-s2.0-85058186835