The relationships between cognitive reserve, cognitive functioning and quality of life in first-episode schizophrenia spectrum disorders
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F22%3A43920802" target="_blank" >RIV/00023752:_____/22:43920802 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/22:10441065 RIV/00216208:11120/22:43923036 RIV/00216208:11210/22:10441065
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0165178122000932?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0165178122000932?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.psychres.2022.114479" target="_blank" >10.1016/j.psychres.2022.114479</a>
Alternative languages
Result language
angličtina
Original language name
The relationships between cognitive reserve, cognitive functioning and quality of life in first-episode schizophrenia spectrum disorders
Original language description
Cognitive reserve (CR) has been conceptualized as an individual’s ability to optimize or maximize performance through differential recruitment of brain networks. As such, CR may contribute to the heterogeneity of cognitive deficits observed in schizophrenia. This study aimed to assess the relationships between CR, cognition and quality of life in first-episode (FES) patients. A total of 137 patients with either ICD-10 schizophrenia or “acute and transient psychotic disorders” diagnosis, and 62 healthy controls had completed a comprehensive assessment of six cognitive domains: speed of processing, attention, working memory/flexibility, verbal memory, visual memory, and abstraction/executive functioning. CR was calculated from the participants’ education, premorbid IQ, and socioeconomic status. The results suggested that in patients, CR was positively related to cognitive performance in all domains, explaining 42.6% of the variance observed in cognition overall. Effects of CR in the control group were limited to three domains: speed of processing, abstraction/executive function and working memory/flexibility. These results suggest that CR largely contributes to cognitive variations present in FES patients. In addition, CR was negatively related to the social construct of patients’ quality of life, and positively to symptom severity and general functioning.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
50103 - Cognitive sciences
Result continuities
Project
<a href="/en/project/GA21-03615S" target="_blank" >GA21-03615S: The Association between Cognition and Cognitive and Brain Reserve in First-Episode Schizophrenia Spectrum Disorders: A Prospective Study</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Psychiatry Research
ISSN
0165-1781
e-ISSN
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Volume of the periodical
310
Issue of the periodical within the volume
"Article Number: 114479"
Country of publishing house
IE - IRELAND
Number of pages
9
Pages from-to
1-9
UT code for WoS article
000829452000040
EID of the result in the Scopus database
2-s2.0-85125247121