Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F23%3A43921176" target="_blank" >RIV/00023752:_____/23:43921176 - isvavai.cz</a>
Alternative codes found
RIV/00216224:90249/23:00133240 RIV/00216208:11240/23:10470442 RIV/00216208:11110/23:10470442 RIV/00216208:11120/23:43926131 RIV/00064173:_____/23:43926131
Result on the web
<a href="https://www.mdpi.com/1718-7729/30/10/652" target="_blank" >https://www.mdpi.com/1718-7729/30/10/652</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/curroncol30100652" target="_blank" >10.3390/curroncol30100652</a>
Alternative languages
Result language
angličtina
Original language name
Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients
Original language description
Background: Cancer-related cognitive impairment (CRCI) is one of the most serious side effects of cancer that negatively impacts the quality of life of cancer patients and survivors. There is evidence of CRCI in Hodgkin lymphoma patients (HL); however, there is a lack of studies examining the presence of cognitive deficits before starting any treatment in HL patients. Methods: Forty adult patients (N = 40) newly diagnosed with HL (with no previous cancer diagnoses) and 40 healthy controls (N = 40) matched for age, sex, education, and premorbid intellect completed the neuropsychological battery and subjective and objective measures of affective distress and quality of life. Results: The results showed impairment in three out of six cognitive domains: verbal memory and learning, speed of processing/psychomotor speed, and abstraction/executive functions in the HL patients before the initiation of any treatment. The speed of processing/psychomotor speed domain is negatively correlated with depression. Conclusion: Cognitive deterioration in verbal memory and learning and abstraction/executive functions domains in HL patients seems to occur before the initiation of treatment independently of anxiety, depression, or physical symptoms. This suggests that HL itself may cause cognitive deficits in these cognitive domains. However, the underlying causes of CRCI still remain unclear. © 2023 by the authors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
50103 - Cognitive sciences
Result continuities
Project
<a href="/en/project/NV16-29857A" target="_blank" >NV16-29857A: Cognitive impairment, structural and functional brain morphological sequelae of Hodgkin lymphoma treatment: Translational study.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Oncology
ISSN
1198-0052
e-ISSN
1718-7729
Volume of the periodical
30
Issue of the periodical within the volume
10
Country of publishing house
CH - SWITZERLAND
Number of pages
11
Pages from-to
9028-9038
UT code for WoS article
001119525500001
EID of the result in the Scopus database
2-s2.0-85175252435