Changes in surgical revascularization strategy after fractional flow reserve

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023884%3A_____%2F21%3A00009130" target="_blank" >RIV/00023884:_____/21:00009130 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/21:00074922 RIV/00216224:14110/21:00123843
Result on the web
<a href="https://onlinelibrary-wiley-com.ezproxy.lib.cas.cz/doi/full/10.1002/ccd.29694" target="_blank" >https://onlinelibrary-wiley-com.ezproxy.lib.cas.cz/doi/full/10.1002/ccd.29694</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ccd.29694" target="_blank" >10.1002/ccd.29694</a>

Result language
angličtina
Original language name
Changes in surgical revascularization strategy after fractional flow reserve
Original language description
Aims In the randomized GRAFFITI trial, surgeons drew their strategy based on coronary angiography. When patients were randomized to fractional flow reserve (FFR)-guidance, surgeons were informed of the FFR values and asked to redraw their strategy. The aim of this study was to investigate the changes induced by FFR knowledge. Methods and Results The intended and performed strategy (before and after FFR) were compared. Among 172 patients, 84 with 300 lesions were randomized to the FFR-guided group. The intended strategy was to bypass 236 stenoses:108 with a venous and 128 with an arterial graft. After disclosing FFR, a change in strategy occurred in 64 lesions (21.3%) of 48 (55%) patients. Among 64 lesions for which the intended strategy was medical therapy, 16 (25%) were bypassed after disclosing FFR. The number of procedures with >1 venous graft planned was significantly reduced from 37 to 27 patients (p = .031). The proportion of on-pump surgery was significantly reduced from 71 to 61 patients (p = .006). The rates of clinical events at 1 year were similar between patients with or without at least one change in strategy. Discussion FFR-guided CABG is associated with a simplified surgical procedure in 55% of the patients, with similar clinical outcomes.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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