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Two mutations in the truncated Rep gene RBR domain delayed the Wheat dwarf virus infection in transgenic barley plants

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F18%3A00004852" target="_blank" >RIV/00027006:_____/18:00004852 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15310/18:73591181

  • Result on the web

    <a href="http://dx.doi.org/10.1016/S2095-3119(18)62000-3" target="_blank" >http://dx.doi.org/10.1016/S2095-3119(18)62000-3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/S2095-3119(18)62000-3" target="_blank" >10.1016/S2095-3119(18)62000-3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Two mutations in the truncated Rep gene RBR domain delayed the Wheat dwarf virus infection in transgenic barley plants

  • Original language description

    Wheat dwarf virus (WDV), an important cereal pathogen, is closely related to Maize streak virus (MSV), a model virus of the Mastrevirus genus. Based on its similarity to known MSV resistance strategies, a truncated part of the WDV replication-associated (RepA) gene (WDVRepA215) and the WDV RepA gene with a mutated retinoblastoma-related protein (RBR) interaction domain (WDVRepA215RBRmut) were cloned into the pIPKb002 expression vector and transformed into immature embryos of spring barley cv. Golden Promise plants through Agrobacterium-mediated transformation. A detailed study of T1-generation plants infected by leafhoppers (Psammotettix alienus) fed on infection sources of variable strength was performed over a 5-week period encompassing the initial stages of virus infection. A DNA WDV TaqMan qPCR assay normalized using the DNA puroindoline-b SYBR Green qPCR assay for samples on a per week basis revealed an approximately 2-week delay in WDVRepA215RBR(mut) plants to WDVRepA215 plants before significant increases in the WDV viral levels occurred. Both WDVRepA215 and WDVRepA215RBRmut plants showed similar levels of transgenic transcripts over the screened period; however, the transgenic plants also showed increased numbers of infected plants compared to the control plants.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Result continuities

  • Project

    <a href="/en/project/LH12161" target="_blank" >LH12161: Functional genomics study of Wheat dwarf virus for the identification of source of resistance and characterization of pathogenicity determinates</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Integrative Agriculture

  • ISSN

    2095-3119

  • e-ISSN

  • Volume of the periodical

    17

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    CN - CHINA

  • Number of pages

    9

  • Pages from-to

    2492-2500

  • UT code for WoS article

    000450126000013

  • EID of the result in the Scopus database

    2-s2.0-85056398519