Nucleolar transplantation and human embryogenesis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F13%3A%230001811" target="_blank" >RIV/00027014:_____/13:#0001811 - isvavai.cz</a>
Result on the web
<a href="http://www.vuzv.cz/sites/File/_privat/13040.pdf" target="_blank" >http://www.vuzv.cz/sites/File/_privat/13040.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-94-007-5818-6_15" target="_blank" >10.1007/978-94-007-5818-6_15</a>
Alternative languages
Result language
angličtina
Original language name
Nucleolar transplantation and human embryogenesis
Original language description
Fully grown mammalian oocytes as well as very early cleavage stage mammalian embryos contain inactive and atypical nucleoli that arc very distinct from nucleoli in stem or differentiated cells. It has been commonly accepted that these nucleoli serve as astorage site of material(s) from which, as the embryo develops, typical active nucleoli are gradually formed. For this reason, these atypical nucleoli are called the nucleolus precursor bodies (NPBs). It has also been demonstrated that the number and distribution of NPBs in pronuclei in human embryos can serve as a simple noninvasive indicator of further embryonic development. The invention of the enucleolation method as well as some recently published results clearly showed some additional roles of NPHs and clarified their Significance in normal embryonic development. In our chapter, these new results will be discussed especially in the context of their use in human assisted reproduction.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GPP302%2F11%2FP069" target="_blank" >GPP302/11/P069: The role of the nucleolus precursor body in oogenesis and early embryonic development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Proteins of the Nucleolus: Regulation, Translocation, & Biomedical Functions
ISBN
9400758170
Number of pages of the result
15
Pages from-to
343-357
Number of pages of the book
377
Publisher name
Springer Science+Business Media
Place of publication
Dordrecht
UT code for WoS chapter
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