Long-term hypocholesterolemic effect of amidated alginate in rats

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F18%3AN0000197" target="_blank" >RIV/00027014:_____/18:N0000197 - isvavai.cz</a>

Result on the web

<a href="https://vuzv.cz/_privat/18196.pdf" target="_blank" >https://vuzv.cz/_privat/18196.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.15407/ubj90.06.120" target="_blank" >10.15407/ubj90.06.120</a>

Result language

angličtina

Original language name

Long-term hypocholesterolemic effect of amidated alginate in rats

Original language description

The effect of octadecylamide of alginic acid on blood serum and hepatic cholesterol, and the faecal output of fat and sterols was examined in female rats fed diets containing cholesterol and palm fat at 10 and 50 g/kg, respectively for 10 weeks. Amidated alginate, supplied at 10 and 20 g/kg, significantly decreased serum cholesterol from 5.25 to 2.99 and 2.39 μmol/ml, respectively, and decreased hepatic cholesterol from 30.7 to 12.3 and 9.4 μmol/g, respectively. Amidated alginate increased the faecal output of fat and at higher dosing significantly decreased faecal output of bile acids. Faecal output of bile acids and hepatic cholesterol significantly correlated (r = 0.791; P < 0.001). The results of the present experiment showed that hypocholesterolemic effect of amidated alginate persisted within 10 weeks of feeding.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Ukrainian biochemical journal

ISSN

2409-4943

e-ISSN

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Volume of the periodical

90

Issue of the periodical within the volume

6

Country of publishing house

UA - UKRAINE

Number of pages

6

Pages from-to

120-125

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85057302712