Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F10%3A%230000606" target="_blank" >RIV/00027162:_____/10:#0000606 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Fertile bull sperm aneuploidy and chromatin integrity in relationship to fertility
Original language description
The purpose of the study was to analyse frequency of aneuploidies of sex chromosomes and chromosome 6 by three-colour FISH in 47 young fertile bulls and to investigate the influence of aneuploidies and disturbed sperm chromatin integrity on non-return rates, the frequencies of abortions, perinatal mortality and stillbirths. Significant correlation was found between sex disomy, total aneuploidy (disomy of chromosomes 6, X, Y and XY sperm and diploidy) and stillbirths (r=0.390; P=0.013; and r=0.331; P=0.037), non-return rate and total aneuploidy (r=-0.310; P=0.036). Chromosome 6 disomy correlated with perinatal mortality (r=0.317; P=0.047). HDS correlated significantly with total aneuploidy (r=0.449; P=0.002). Our study indicated that aneuploidy frequencies in young fertile bull sperm are relatively low. Nevertheless, there exists a variability in aneuploidy frequencies amongst bulls, which appears to be able to have an influence on the fertility of these animals.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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