Porcine mononuclear phagocyte subpopulations in the lung, blood and bone marrow: dynamics during inflammation induced by Actinobacillus pleuropneumoniae

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F10%3A%230000640" target="_blank" >RIV/00027162:_____/10:#0000640 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Porcine mononuclear phagocyte subpopulations in the lung, blood and bone marrow: dynamics during inflammation induced by Actinobacillus pleuropneumoniae

Original language description

The present study was aimed at describing porcine mononuclear phagocyte subpopulations infiltrating inflamed tissue of pigs under in vivo conditions. Actinobacillus pleuropneumoniae infection was used to induce an inflammatory response. CD172a, CD14, CD163, MHCII and CD203a cell surface molecules were used to identify mononuclear phagocyte by flow cytometry. Changes in mononuclear phagocyte subpopulations in the peripheral blood and bone marrow compartments along with the analysis of mononuclear phagocyte appearing in the inflamed lungs were assessed to elucidate the possible origin and maturation stages of the infiltrating mononuclear phagocyte. The mononuclear phagocyte population migrating to the inflamed lungs was positive for molecules CD14 and CD163 and positive or negative for molecules CD203a and MHCII. Based on results, two different maturation pathways of mononuclear phagocyte were suggested in pigs. The use of these pathways differs under inflammatory and non-inflammatory co

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinary Research

ISSN

0928-4249

e-ISSN

—

Volume of the periodical

41

Issue of the periodical within the volume

5

Country of publishing house

FR - FRANCE

Number of pages

14

Pages from-to

—

UT code for WoS article

000284063300009

EID of the result in the Scopus database

—