Genetic basis of resistance to quaternary ammonium compounds - the qac genes and their role: a review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F12%3A%230000913" target="_blank" >RIV/00027162:_____/12:#0000913 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Genetic basis of resistance to quaternary ammonium compounds - the qac genes and their role: a review

Original language description

Although the qac genes are named after one of their main substrates (i.e. quaternary ammonium compounds), these also encode for resistance to a broad spectrum of other cationic compounds such as intercalating dyes, diamidines and biguanides. The variousQac proteins are involved in relatively low specific efflux-based multidrug pumps and belong to a family of small multidrug resistance proteins. Even though the practical significance of qac-mediated resistance lies mainly in resistance to antiseptics, contradictory findings on this topic are still reported. Therefore, the aim of this review was to summarise the current knowledge on the qac-mediated resistance with special emphasise on resistance to antiseptics and its relevance for practice.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GM - Food industry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinární Medicína

ISSN

0375-8427

e-ISSN

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Volume of the periodical

57

Issue of the periodical within the volume

6

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

275-281

UT code for WoS article

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EID of the result in the Scopus database

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