The phenotype and activation status of T and NK cells in porcine colostrum suggest these are central/effector memory cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F14%3A%230001101" target="_blank" >RIV/00027162:_____/14:#0001101 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.tvjl.2014.09.008" target="_blank" >http://dx.doi.org/10.1016/j.tvjl.2014.09.008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tvjl.2014.09.008" target="_blank" >10.1016/j.tvjl.2014.09.008</a>

Result language
angličtina
Original language name
The phenotype and activation status of T and NK cells in porcine colostrum suggest these are central/effector memory cells
Original language description
In pigs, the epitheliochorial placenta does not allow transfer of maternally derived antibodies or immune cells to the fetus. Thus, piglets are dependent on intake of colostrum for acquisition of passive immunity during the neonatal period. As well as immunoglobulin G (IgG), cellular components of colostrum, mainly lymphocytes, can enter the systemic circulation and secondary lymphoid organs of the neonate. In order to understand the function and immunological role of these cells, a flow cytometric study was undertaken to characterise the cellular profile and phenotype of T cells and NK cells present in porcine colostrum. The results indicated that the greatest numbers of lymphocytes were found on the first day of lactation. The predominant cell typesin colostrum were CD8(+) single positive T cells (53.6%), followed by CD4(+)CD8(+) double positive T cells (21.1%), CD2(+)CD8(+) gamma delta T cells (15.0%) and NK cells (13.5%). CD4(+) single positive T cells (4.4%) and other gamma delta
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Project
<a href="/en/project/LO1218" target="_blank" >LO1218: Healthy animal as a source of wholesome food</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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