Effect of dietary fish oil on selected markers of an inflammatory status in pigs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F16%3AN0000146" target="_blank" >RIV/00027162:_____/16:N0000146 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/16:43910213

Result on the web

<a href="https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effect of dietary fish oil on selected markers of an inflammatory status in pigs

Original language description

The objective of the experiment was to test a hypothesis that the biologically active substances present in fish oil (eicosapentaenoic acid, EPA, and docosahexaenoic acid, DHA) are able to stabilize inflammatory status in an organism. Thirty two pigs (Large White x Landrace) at the age of eight weeks with the mean live weight of 25.5 kg were used as a model organism. The pigs were divided into two groups with 16 animals each; the experimental and control group was fed the basic feed mixture with 2.5% of fish oil (F) and 2.5% of palm oil (P), respectively. The F - and P - pigs were randomly divided into two groups 70th day of fattening, and eight F - and eight P - pigs were treated with E. coli lipopolysaccharide (LPS). After anesthetizing, pigs were sacrificed by bleeding, the blood and liver samples were taken, and expression of the liver genes coding for 7 selected cytokines and plasma concentration of adiponectin and three cytokines was determined. No significant effect (P > 0.05) of dietary intervention on feed intake, live weight and live weight gain was found. Fish oil tended to increase (P > 0.05) relative expression of all tested cytokine genes, the effect being significant (P < 0.05) in the case of IL - 6 and TGF - beta 1 after LPS application. Fish oil also increased (P < 0.05) plasma concentration of TNF alpha in pigs treated with LPS. On the other hand, fish oil tended to decrease (P = 0.22) plasma adiponectin in comparison with palm oil. The present study did not confirm anti-inflammatory effect of fish oil.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

MendelNet 2016

ISBN

978-80-7509-443-8

ISSN

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e-ISSN

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Number of pages

5

Pages from-to

819-823

Publisher name

Mendelova Univerzita v Brně

Place of publication

Brno

Event location

Brno

Event date

Nov 9, 2016

Type of event by nationality

EUR - Evropská akce

UT code for WoS article

000392968500147