Effect of dietary fish oil on selected inflammatory markers in pigs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F18%3AN0000203" target="_blank" >RIV/00027162:_____/18:N0000203 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/18:43914079

Result on the web

<a href="https://www.cambridge.org/core/journals/animal/article/effect-of-dietary-fish-oil-on-selected-inflammatory-markers-in-pigs/47F3DA31C12C48A5FFAE2B0F8DF7D5EA" target="_blank" >https://www.cambridge.org/core/journals/animal/article/effect-of-dietary-fish-oil-on-selected-inflammatory-markers-in-pigs/47F3DA31C12C48A5FFAE2B0F8DF7D5EA</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/S1751731117003767" target="_blank" >10.1017/S1751731117003767</a>

Result language

angličtina

Original language name

Effect of dietary fish oil on selected inflammatory markers in pigs

Original language description

The present study tested a hypothesis that dietary fish oil (eicosapentaenoic acid and docosahexaenoic acid) in a commonly achievable dose ameliorates a systemic inflammation in pigs. Two groups of pigs of 16 animals each were fed a diet with either 2.5% of fish oil (F) or a control diet with 2.5% of palm oil (P). After 70 days of fattening, eight F and eight P pigs were challenged i.v. by lipopolysaccharide. After 3 h, all pigs were sacrificed and blood, liver and visceral adipose tissue (VAT) samples were taken. No significant effect (P>0.05) of dietary oil on the feed intake and daily weight gain was found out. Less neutrophils (16.8% v. 28.8%; P<0.05) were found in the F+-leukocytes of the peripheral blood; F+ pigs had lower (P<0.05) percentage of the swine leukocyte antigen-D-related CD163+ (SLA-DR+ CD163+) macrophages in the VAT (15.4% v. 21.8%) and lower expression of the SLA-DR-CD163+ surface molecules of the VAT macrophages. No difference (P>0.05) between F+ and P+ pigs in the peroxisome proliferator-activated receptor γ, GPR120, Adipor1 and Adipor2 (adiponectin receptor) gene expression, respectively, was established; plasma adiponectin was the same (21.1 ng/ml) in F+ and P+ pigs. In comparison with the P+ pigs, increased expression of the lipopolysaccharide-binding protein (LBP) gene and intercellular adhesion molecule 1 (ICAM1) gene was found out in the liver of the F+ pigs; expression of the tumor necrosis factor α (TNFα) gene was higher in the liver but lower in the VAT of the F+ pigs (P<0.05). The F+ pigs had higher (P<0.05) plasma concentration of both anti-inflammatory cytokine interleukin-4 (0.46 v. 0.04 ng/ml) and pro-inflammatory TNF-α (13.41 v. 7.72 ng/ml). It was concluded that dietary fish oil at the tested amount had a negligible effect on expression of the evaluated receptor genes and plasma adiponectin, and had an ambiguous effect on expression of cytokine genes and plasma cytokine levels.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40301 - Veterinary science

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Animal

ISSN

1751-7311

e-ISSN

1751-732X

Volume of the periodical

12

Issue of the periodical within the volume

10

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

2098-2107

UT code for WoS article

000451915600014

EID of the result in the Scopus database

—