Modification of Liposomal Surface by Polysacharides: Preparation, Characterization and Appliccation for Drug Targeting – chapter 13
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F19%3AN0000292" target="_blank" >RIV/00027162:_____/19:N0000292 - isvavai.cz</a>
Result on the web
<a href="https://www.elsevier.com/books/functional-polysaccharides-for-biomedical-applications/maiti/978-0-08-102555-0" target="_blank" >https://www.elsevier.com/books/functional-polysaccharides-for-biomedical-applications/maiti/978-0-08-102555-0</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Modification of Liposomal Surface by Polysacharides: Preparation, Characterization and Appliccation for Drug Targeting – chapter 13
Original language description
Polysaccharides are indispensable macromolecules widely used in pharmaceutical industry. Hyaluronic acid, mannans, cellulose derivatives, alginates and, dextrans are applied for preparation of polysaccharide-modified nanoparticles to develop targeted delivery systems for drugs, theranostics, vaccines and immunotherapeutics. Liposomes represent the most versatile nanoparticles and liposomal products have already found clinical applications, due to their biocompatibility, biodegradability, low toxicity and ability to internalize substances with different physical-chemical properties. Modification of liposomal surface with polysaccharides is a special part of bioconjugation chemistry and application of click chemistry for orthogonal binding of polysaccharides onto liposomal surface is new challenging approach for development of drug and vaccine targeting nanosystems. New technologies for laboratory and industrial production of polysaccharide-modified liposomes can be developed by combination of microfluidics technology integrated together with other processes (dialysis, click chemistry, photochemistry, and drug loading) into a single device by utilizing so-called Lab-on-Chip technology enabling automated high-throughput processes for production of liposome-based products.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
21001 - Nano-materials (production and properties)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Functional Polysaccharides for Biomedical Applications
ISBN
9780081025550
Number of pages of the result
35
Pages from-to
433-467
Number of pages of the book
526
Publisher name
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Place of publication
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UT code for WoS chapter
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