The impact of parturition induction with cloprostenol on immunological parameters in the sow colostrum
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F20%3AN0000200" target="_blank" >RIV/00027162:_____/20:N0000200 - isvavai.cz</a>
Result on the web
<a href="https://porcinehealthmanagement.biomedcentral.com/articles/10.1186/s40813-020-00174-y" target="_blank" >https://porcinehealthmanagement.biomedcentral.com/articles/10.1186/s40813-020-00174-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s40813-020-00174-y" target="_blank" >10.1186/s40813-020-00174-y</a>
Alternative languages
Result language
angličtina
Original language name
The impact of parturition induction with cloprostenol on immunological parameters in the sow colostrum
Original language description
Background Farrowing induction with prostaglandin F2 analogue cloprostenol is commonly used on commercial farms to manage the timing of farrowing. When labour induction is applied, the questions arise about possible side effects of such a hormonal intervention on physiological processes connected with labour and lactation, including colostral immunity. Results In this study, immune cells composition, lysozyme concentration, complement bacteriolytic activity and proinflamatory (GM-CSF2, IL-1 beta, IL-6, a TNF alpha) and anti-inflammatory (IL-4, IL-10, TGF beta 1 a TGF beta 2) cytokines were measured in colostrum samples from sows farrowing naturally (NP) and from sows with farrowing induced using cloprostenol administration on day 113 of gestation (IP). A significantly higher proportion of lymphocytes was found in colostrum of induced sows compared to colostrum of non-induced sows. No significant differences between NP and IP were found in complement activity, in the proportions of granulocytes, macrophages and lymphocyte subpopulations. Lower lysozyme concentration and higher IL-1 beta, IL-6, TGF beta 1 and TNF alpha concentrations were found in IP sow colostrum compared to colostrum from NP sows. Conclusions An increased proportion of colostral lymphocytes can positively influence the cellular immunity transmission from sow to her offspring. On the other hand, a lower lysozyme concentration can adversely affect newborn's intestinal immunity, as well as changes in cytokine concentrations can have an adverse effect on newborn piglet intestinal epithelium development and its defence function.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PORCINE HEALTH MANAGEMENT
ISSN
2055-5660
e-ISSN
2055-5660
Volume of the periodical
6
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
"35"
UT code for WoS article
000597627800001
EID of the result in the Scopus database
2-s2.0-85097374030