Arteriovenous differences of hematological and coagulation parameters in patients with sepsis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F10%3A6515" target="_blank" >RIV/00064165:_____/10:6515 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/10:6330 RIV/00064203:_____/10:6330
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Arteriovenous differences of hematological and coagulation parameters in patients with sepsis
Original language description
In critically ill patients, arterial or venous blood is available for sampling and measurement of coagulation parameters. The aim of this study was to examine whether in these patients the values of coagulation parameters differ with respect to the source of the blood samples. In patients with severe sepsis, we compared the values of coagulation, thromboelastography and selected hematological parameters between the arterial and venous blood. In most of the investigated parameters (INR, APTT, fibrinogen,erythrocyte, leukocyte and platelet count, hemoglobin level and thromboelastography parameters), we did not find differences (P>0.1). However, we found lower antithrombin activity and higher D-dimer concentration in venous blood compared to arterial blood (P<0.05). It could be associated with increased consumption of antithrombin and generation of D-dimer as a consequence of microthrombi formation in the capillaries. In this case, arterial and venous blood cannot be treated as equivalen
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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