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PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F13%3A10210260" target="_blank" >RIV/00064165:_____/13:10210260 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/13:10210260

  • Result on the web

    <a href="http://www.chemicke-listy.cz/docs/full/2013_s3_s420-s453.pdf" target="_blank" >http://www.chemicke-listy.cz/docs/full/2013_s3_s420-s453.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    PLASMA FREE METANEPHRINES AS DIAGNOSTIC MARKERS OF PHEOCHROMOCYTOMA

  • Original language description

    Quantitative determination of catecholamines and their O-methyl metabolites plays an important role in the diagnosis of pheochromocytoma (PHEO) - adrenal medulla tumour. This kind of tumour synthesizes, stocks, metabolizes and mostly secretes catecholamines. For this reason it is possible to use elevated concentrations of catecholamines and their metabolic products from plasma and urine as diagnostic markers of this tumour. Determination of metanephrines is often preferred against determination of catecholamines regarding the diagnosis of PHEO. Tumour cells produce free metanephrines continuously and irrespective of the release of catecholamines. The project aims to develop a new kit for the determination of plasma metanephrines. Solid phase extraction(SPE) was used for the pre-treatment of plasma samples. The determination was performed by high performance liquid chromatography with electrochemical detection (HPLC-ED).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/FR-TI4%2F331" target="_blank" >FR-TI4/331: *The development of a plasma free metanephrine analysis kit</a><br>

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemické listy

  • ISSN

    0009-2770

  • e-ISSN

  • Volume of the periodical

    107

  • Issue of the periodical within the volume

    Supplement 3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    3

  • Pages from-to

    "S420"-"S422"

  • UT code for WoS article

    000328730800056

  • EID of the result in the Scopus database