HMGB1, S100 proteins and other RAGE ligands in cancer - markers, mediators and putative therapeutic targets

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10324549" target="_blank" >RIV/00064165:_____/16:10324549 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/16:10324549

Result on the web

<a href="http://biomed.papers.upol.cz/pdfs/bio/2016/01/01.pdf" target="_blank" >http://biomed.papers.upol.cz/pdfs/bio/2016/01/01.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2016.003" target="_blank" >10.5507/bp.2016.003</a>

Result language

angličtina

Original language name

HMGB1, S100 proteins and other RAGE ligands in cancer - markers, mediators and putative therapeutic targets

Original language description

Background and Aims. Activation of RAGE due to its increased expression in cancer cells or its stimulation by multiple ligands (AGEs, HMGB1, S100 proteins, etc.) may contribute to the proliferation, invasiveness of tumor cells and formation of distant metastases and also to the resistance of cancer to treatment. RAGE ligands could thus become both useful markers of disease severity and its outcome and, a potential therapeutic target. Conclusions. Better understanding of the role of RAGE activation in different types of cancer may help to define the role of ligand/RAGE antagonists as promising cancer treatment.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers

ISSN

1213-8118

e-ISSN

—

Volume of the periodical

160

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

1-10

UT code for WoS article

000373390800001

EID of the result in the Scopus database

2-s2.0-84962469623