Independent and sensory human mitochondrial functions reflecting symbiotic evolution
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F23%3A10466155" target="_blank" >RIV/00064165:_____/23:10466155 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10466155
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=_YGh.DeX65" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=_YGh.DeX65</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fcimb.2023.1130197" target="_blank" >10.3389/fcimb.2023.1130197</a>
Alternative languages
Result language
angličtina
Original language name
Independent and sensory human mitochondrial functions reflecting symbiotic evolution
Original language description
The bacterial origin of mitochondria has been a widely accepted as an event that occurred about 1.45 billion years ago and endowed cells with internal energy producing organelle. Thus, mitochondria have traditionally been viewed as subcellular organelle as any other - fully functionally dependent on the cell it is a part of. However, recent studies have given us evidence that mitochondria are more functionally independent than other organelles, as they can function outside the cells, engage in complex "social" interactions, and communicate with each other as well as other cellular components, bacteria and viruses. Furthermore, mitochondria move, assemble and organize upon sensing different environmental cues, using a process akin to bacterial quorum sensing. Therefore, taking all these lines of evidence into account we hypothesize that mitochondria need to be viewed and studied from a perspective of a more functionally independent entity. This view of mitochondria may lead to new insights into their biological function, and inform new strategies for treatment of disease associated with mitochondrial dysfunction.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Cellular and Infection Microbiology
ISSN
2235-2988
e-ISSN
2235-2988
Volume of the periodical
13
Issue of the periodical within the volume
June
Country of publishing house
CH - SWITZERLAND
Number of pages
11
Pages from-to
1130197
UT code for WoS article
001018199900001
EID of the result in the Scopus database
2-s2.0-85163776542