Re: Laura Elst, Gino Philips, Kaat Vandermaesen, et al. Single-cell Atlas of Penile Cancer Reveals TP53 Mutations as a Driver of an Aggressive Phenotype, Irrespective of Human Papillomavirus Status, and Provides Clues for Treatment Personalization. Eur Urol. 2024;86:114-27
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43927460" target="_blank" >RIV/00064173:_____/24:43927460 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/24:10483493 RIV/00216208:11120/24:43927460 RIV/00064165:_____/24:10483493
Result on the web
<a href="https://doi.org/10.1016/j.eururo.2024.07.029" target="_blank" >https://doi.org/10.1016/j.eururo.2024.07.029</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.eururo.2024.07.029" target="_blank" >10.1016/j.eururo.2024.07.029</a>
Alternative languages
Result language
angličtina
Original language name
Re: Laura Elst, Gino Philips, Kaat Vandermaesen, et al. Single-cell Atlas of Penile Cancer Reveals TP53 Mutations as a Driver of an Aggressive Phenotype, Irrespective of Human Papillomavirus Status, and Provides Clues for Treatment Personalization. Eur Urol. 2024;86:114-27
Original language description
Our results provide deeper insight into pSCC biology as they corroborate those published by Elst et al in a large retrospective cohort showing utility in routine praxis. We confirmed mutated TP53 as a key marker of poor prognosis in pSCC owing to its association with EMT, which is detectable histopathologically as tumor budding. Thus, we propose use of these markers in routine pSCC diagnostics.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30109 - Pathology
Result continuities
Project
<a href="/en/project/NU21J-03-00019" target="_blank" >NU21J-03-00019: The prognostic predictive markers in penile carcinoma: a molecular and morphological study.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Urology
ISSN
0302-2838
e-ISSN
1873-7560
Volume of the periodical
86
Issue of the periodical within the volume
6
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
2
Pages from-to
"e145"-"e146"
UT code for WoS article
001386187800001
EID of the result in the Scopus database
2-s2.0-85203066743