Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F16%3AN0000048" target="_blank" >RIV/00064190:_____/16:N0000048 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00401-015-1509-x" target="_blank" >http://dx.doi.org/10.1007/s00401-015-1509-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00401-015-1509-x" target="_blank" >10.1007/s00401-015-1509-x</a>

Result language
angličtina
Original language name
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
Original language description
Pathological accumulation of abnormally phosphorylated tau protein in astrocytes is a frequent, but poorly characterized feature of the aging brain. Its etiology is uncertain, but its presence is sufficiently ubiquitous to merit further characterization and classification, which may stimulate clinicopathological studies and research into its pathobiology. This paper aims to harmonize evaluation and nomenclature of aging-related tau astrogliopathy (ARTAG), a term that refers to a morphological spectrum of astroglial pathology detected by tau immunohistochemistry, especially with phosphorylation-dependent and 4R isoform-specific antibodies.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/NT12094" target="_blank" >NT12094: Multidisciplinary approach in the diagnosis of frontotemporal lobar degenerations and tauopathies: new insights into pathogenetic mechanisms</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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