Hydration and Transparency of the Rabbit Cornea Irradiated with UVB-Doses of 0.25 J/cm(2) and 0.5 J/cm(2) Compared with Equivalent UVB Radiation Exposure Reaching the Human Cornea from Sunlight

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7049" target="_blank" >RIV/00064203:_____/11:7049 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/11:00366472 RIV/61389013:_____/11:00366472 RIV/00216208:11120/11:00003322 RIV/00216208:11130/11:7049
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/21599489" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21599489</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Hydration and Transparency of the Rabbit Cornea Irradiated with UVB-Doses of 0.25 J/cm(2) and 0.5 J/cm(2) Compared with Equivalent UVB Radiation Exposure Reaching the Human Cornea from Sunlight
Original language description
Purpose: Exposure of the cornea to UV radiation from sunlight evokes intraocular inflammation, photokeratitis. Photokeratitis is caused by UVB radiation. It is accompanied by changes of corneal hydration and light absorption. The aim of this study was toexamine the effect of two UVB doses on corneal optics in rabbits and to compare these UVB doses with the equivalent exposure of UVB radiation reaching the human cornea from sunlight. Materials and Methods: Rabbit corneas were irradiated with a daily UVBdose of 0.25 J/cm(2) or 0.5 J/cm(2) for 4 days. One day after finishing the irradiations the rabbits were sacrificed and corneal light absorption measured using our spectrophotometrical method. Corneal hydration was examined using an ultrasonic Pachymeter every experimental day before the irradiation procedure and the last day before sacrificing the animals. Results: Changes in corneal optics appeared after the repeated exposure of the cornea to a UVB dose of 0.25 J/cm(2) and massively
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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