The Reversibility of UV-B Induced Alterations in Optical Properties of the Rabbit Cornea Depends on Dose of UV Irradiation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F13%3A43907250" target="_blank" >RIV/00216208:11120/13:43907250 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/13:00390181 RIV/61389013:_____/13:00390181 RIV/68407700:21460/13:00202593 RIV/00216208:11130/13:10209771 RIV/00064203:_____/13:10209771
Result on the web
<a href="http://dx.doi.org/10.1111/php.12010" target="_blank" >http://dx.doi.org/10.1111/php.12010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/php.12010" target="_blank" >10.1111/php.12010</a>
Alternative languages
Result language
angličtina
Original language name
The Reversibility of UV-B Induced Alterations in Optical Properties of the Rabbit Cornea Depends on Dose of UV Irradiation
Original language description
Solar UVB radiation evokes photokeratitis, accompanied by increased corneal hydration and changes in corneal transparency, resulting in increased light absorption. Corneal optical properties are disturbed and visual acuity decreased. The aim of this study was to investigate the reversibility of these UVB-induced changes. Rabbit corneas were irradiated with UVB doses of 0.5Jcm2 or 1.01Jcm2 during 4days. Some rabbits were sacrificed after the last irradiation and some 2months later. Corneas were investigated spectrophotometrically for light absorption, and corneal hydration was evaluated by central corneal thickness with an ultrasonic pachymeter. Corneal impression cytologies were examined immunohistochemically for proinflammatory cytokines and malondialdehyde. The increased corneal light absorption, hydration and the staining of immunohistochemical markers found in corneas after irradiation returned to normal values during 2months in corneas irradiated with the lower UVB dose. In contra
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Photochemistry and Photobiology
ISSN
0031-8655
e-ISSN
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Volume of the periodical
89
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
474-482
UT code for WoS article
000315644100026
EID of the result in the Scopus database
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