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Micronuclei levels in mothers and their newborns from regions with different types of air pollution

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7155" target="_blank" >RIV/00064203:_____/11:7155 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/11:00365843 RIV/00216208:11130/11:7155

  • Result on the web

    <a href="http://www.ncbi.nlm.nih.gov/pubmed/21827774" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21827774</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Micronuclei levels in mothers and their newborns from regions with different types of air pollution

  • Original language description

    The aim of this study was to analyze genetic damage in human lymphocytes measured using automated image analysis of micronuclei (MN) in a group of 178 mothers and their newborns from two locations in the Czech Republic. The concentrations of benzo[a]pyrene (B[a]B), particulate matter of aerodynamic diameter <2.5 mu m (PM2.5) and benzene were measured by stationary monitoring in the winter season of 2008/2009 in the capital city of Prague and in Ceske Budejovice, a regional city in a rural area. The 3-month mean concentration of B[a]P before delivery was lower in Prague in comparison with Ceske Budejovice: 1.9 +/- 0.5 ng/m(3) vs. 3.2 +/- 0.2 ng/m(3) (p < 0.001). The opposite trend was found for PM2.5 and benzene: 27.0 +/- 2.5 mu g/m(3) and 2.5 +/- 0.5 mu g/m(3) vs. 24.5 +/- 0.7 mu g/m(3) and 2.1 +/- 0.8 mu g/m(3) (p < 0.001) for Prague vs. Ceske Budejovice, respectively. The average age of the mothers was 31 years (range, 18-49 years). The frequencies of MN per 1000 binucleated cells we

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/2B06088" target="_blank" >2B06088: Application of toxicogenomics to study mechanisms of the action of environmental pollutants on human health.</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis

  • ISSN

    0027-5107

  • e-ISSN

  • Volume of the periodical

    715

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    72-78

  • UT code for WoS article

    000295664200010

  • EID of the result in the Scopus database