The role of connexin 37 gene polymorphism (1019C > T; pro319ser) in cardiovascular disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7253" target="_blank" >RIV/00064203:_____/11:7253 - isvavai.cz</a>

Alternative codes found

RIV/00023001:_____/11:00002578 RIV/00216208:11130/11:7253

Result on the web

<a href="http://www.doaj.org/doaj?func=abstract&id=746736" target="_blank" >http://www.doaj.org/doaj?func=abstract&id=746736</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The role of connexin 37 gene polymorphism (1019C > T; pro319ser) in cardiovascular disease

Original language description

In spite of the strong prognostic value of all traditional cardiovascular risk factors, still striking differences exist in the prevalence of clinical events between patients at apparently similar risk. One of the main reasons is different genetic background. One of recently discussed candidate genes for cardiovascular disease is the gene for the protein Connexin 37 (Cx37). This protein is a part of gap junctions responsible for communications between cells including cells in the vessel wall. Studies focused on the association between Cx37 gene polymorphism (1019C > T; Pro319Ser) and cardiovascular disease demonstrate inconsistent results. Our findings in 1.316 men and women indicated that the Cx37 gene polymorphism (genotype CC) is significantly associated with acute coronary syndrome in non-smoking women. In addition, in urban and rural women from general population (n = 1.056) with impaired fasting glycaemia the same genotype is associated with increased intima media thickness of ca

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/1M0510" target="_blank" >1M0510: Centre for cardiovascular research</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biopolymers and Cell

ISSN

0233-7657

e-ISSN

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Volume of the periodical

27

Issue of the periodical within the volume

2

Country of publishing house

UA - UKRAINE

Number of pages

6

Pages from-to

118-123

UT code for WoS article

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EID of the result in the Scopus database

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