Assays for determination of matrix metalloproteinases and their activity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7596" target="_blank" >RIV/00064203:_____/11:7596 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/11:00180506 RIV/00216305:26620/11:PU95556 RIV/00216208:11310/11:10107196 RIV/00216208:11130/11:7596 RIV/00216224:14110/11:00056993
Result on the web
<a href="http://dx.doi.org/10.1016/j.trac.2011.06.016" target="_blank" >http://dx.doi.org/10.1016/j.trac.2011.06.016</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Assays for determination of matrix metalloproteinases and their activity
Original language description
Matrix metalloproteinases (MMPs) are involved in many physiological and pathological processes. Due to their ability to cleave and to remodel components of surrounding tissues, MMPs may affect cell migration, differentiation, growth, inflammatory processes, neovascularization, wound healing, apoptosis, the uterine cycle and many other actions within the body, including those needed for tumorigenesis and other diseases. MMPs can therefore be used as potential markers for detecting various cancers, neurodegenerative, and immune and cardiovascular diseases. Numerous MMP assays were developed for clinical and research purposes, but far more attention has been devoted to understanding their biological functions. Due to differences in methodology, results obtained in various laboratory settings are difficult to compare because of the lack of standards and analytical methods of validation. Limits of detection of particular methods used for identifying MMPs are also disputable. Enzymatic, immu
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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