A new survival score for patients with brain metastases who received whole-brain radiotherapy (WBRT) alone

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F13%3A10294183" target="_blank" >RIV/00064203:_____/13:10294183 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/13:10294183
Result on the web
<a href="http://dx.doi.org/10.1016/j.radonc.2013.06.009" target="_blank" >http://dx.doi.org/10.1016/j.radonc.2013.06.009</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.radonc.2013.06.009" target="_blank" >10.1016/j.radonc.2013.06.009</a>

Result language
angličtina
Original language name
A new survival score for patients with brain metastases who received whole-brain radiotherapy (WBRT) alone
Original language description
Background and purpose: Survival scores for patients with brain metastasis exist. However, the treatment regimens used to create these scores were heterogeneous. This study aimed to develop and validate a survival score in homogeneously treated patients.Materials and methods: Eight-hundred-and-eighty-two patients receiving 10 x 3 Gy of WBRT alone were randomly assigned to a test group (N = 441) or a validation group (N = 441). In the multivariate analysis of the test group, age, performance status, extracranial metastasis, and systemic treatment prior to WBRT were independent predictors of survival. The score for each factor was determined by dividing the 6-month survival rate (in %) by 10. Scores were summed and total scores ranged from 6 to 19 points. Patients were divided into four prognostic groups. Results: The 6-month survival rates were 4% for 6-9 points, 29% for 10-14 points, 62% for 15-17 points, and 93% for 17-18 points (p < 0.001) in the test group. The survival rates were
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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