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Shorter-Course Whole-Brain Radiotherapy for Brain Metastases in Elderly Patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A10294185" target="_blank" >RIV/00064203:_____/11:10294185 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/11:10294185

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.ijrobp.2011.01.058" target="_blank" >http://dx.doi.org/10.1016/j.ijrobp.2011.01.058</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ijrobp.2011.01.058" target="_blank" >10.1016/j.ijrobp.2011.01.058</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Shorter-Course Whole-Brain Radiotherapy for Brain Metastases in Elderly Patients

  • Original language description

    Purpose: Many patients with brain metastases receive whole-brain radiotherapy (WBRT) alone. Using 10 x 3 Gy in 2 weeks is the standard regimen in most centers. Regarding the extraordinarily poor survival prognosis of elderly patients with multiple brainmetastases, a shorter WBRT regimen would be preferable. This study compared 10 x 3 Gy with 5 x 4 Gy in elderly patients (}= 65 years). Methods and Materials: Data from 455 elderly patients who received WBRT alone for brain metastases were retrospectivelyanalyzed. Survival and local (= intracerebral) control of 293 patients receiving 10 x 3 Gy were compared with 162 patients receiving 5 x 4 Gy. Eight additional potential prognostic factors were investigated including age, gender, Karnofsky performance score (KPS), primary tumor, number of brain metastases, interval from tumor diagnosis to WBRT, extracerebral metastases, and recursive partitioning analysis (RPA) class. Results: The 6-month overall survival rates were 29% after 5 x 4 Gy a

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Radiation Oncology Biology Physics

  • ISSN

    0360-3016

  • e-ISSN

  • Volume of the periodical

    81

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    "E469"-"E473"

  • UT code for WoS article

    000309412300035

  • EID of the result in the Scopus database