Shorter-Course Whole-Brain Radiotherapy for Brain Metastases in Elderly Patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A10294185" target="_blank" >RIV/00064203:_____/11:10294185 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/11:10294185
Result on the web
<a href="http://dx.doi.org/10.1016/j.ijrobp.2011.01.058" target="_blank" >http://dx.doi.org/10.1016/j.ijrobp.2011.01.058</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijrobp.2011.01.058" target="_blank" >10.1016/j.ijrobp.2011.01.058</a>
Alternative languages
Result language
angličtina
Original language name
Shorter-Course Whole-Brain Radiotherapy for Brain Metastases in Elderly Patients
Original language description
Purpose: Many patients with brain metastases receive whole-brain radiotherapy (WBRT) alone. Using 10 x 3 Gy in 2 weeks is the standard regimen in most centers. Regarding the extraordinarily poor survival prognosis of elderly patients with multiple brainmetastases, a shorter WBRT regimen would be preferable. This study compared 10 x 3 Gy with 5 x 4 Gy in elderly patients (}= 65 years). Methods and Materials: Data from 455 elderly patients who received WBRT alone for brain metastases were retrospectivelyanalyzed. Survival and local (= intracerebral) control of 293 patients receiving 10 x 3 Gy were compared with 162 patients receiving 5 x 4 Gy. Eight additional potential prognostic factors were investigated including age, gender, Karnofsky performance score (KPS), primary tumor, number of brain metastases, interval from tumor diagnosis to WBRT, extracerebral metastases, and recursive partitioning analysis (RPA) class. Results: The 6-month overall survival rates were 29% after 5 x 4 Gy a
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Radiation Oncology Biology Physics
ISSN
0360-3016
e-ISSN
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Volume of the periodical
81
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
"E469"-"E473"
UT code for WoS article
000309412300035
EID of the result in the Scopus database
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