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Febrile urinary tract infection after pediatric kidney transplantation: a multicenter, prospective observational study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10323773" target="_blank" >RIV/00064203:_____/16:10323773 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/16:10323773

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s00467-015-3292-2" target="_blank" >http://dx.doi.org/10.1007/s00467-015-3292-2</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00467-015-3292-2" target="_blank" >10.1007/s00467-015-3292-2</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Febrile urinary tract infection after pediatric kidney transplantation: a multicenter, prospective observational study

  • Original language description

    Febrile urinary tract infections (fUTIs) are common after kidney transplantation (KTx); however, prospective data in a multicenter pediatric cohort are lacking. We designed a prospective registry to record data on fUTI before and after pediatric KTx. Ninety-eight children (58 boys and 40 girls) a parts per thousand currency signaEuro parts per thousand 18 years from 14 mid-European centers received a kidney transplant and completed a 2-year follow-up. Posttransplant, 38.7 % of patients had at least one fUTI compared with 21.4 % before KTx (p = 0.002). Before KTx, fUTI was more frequent in patients with congenital anomalies of kidneys and urinary tract (CAKUT) vs. patients without (38 % vs. 12 %; p = 0.005). After KTx, fUTI were equally frequent in both groups (48.7 % vs. 32.2 %; p = 0.14). First fUTI posttransplant occurred earlier in boys compared with girls: median range 4 vs. 13.5 years (p = 0.002). Graft function worsened (p < 0.001) during fUTI, but no difference was recorded after 2 years. At least one recurrence of fUTI was encountered in 58 %. This prospective study confirms a high incidence of fUTI after pediatric KTx, which is not restricted to patients with CAKUT; fUTIs have a negative impact on graft function during the infectious episode but not on 2-year graft outcome.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FG - Paediatrics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Pediatric Nephrology

  • ISSN

    0931-041X

  • e-ISSN

  • Volume of the periodical

    31

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    1021-1028

  • UT code for WoS article

    000374579700016

  • EID of the result in the Scopus database

    2-s2.0-84954112575