Stability of Non-Activated Rotational Thromboelastometry Assay in Time of Citrated Blood (Appropriate Time Interval for Analysis)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10332580" target="_blank" >RIV/00064203:_____/16:10332580 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/16:10332580
Result on the web
<a href="http://dx.doi.org/10.7754/Clin.Lab.2016.160328" target="_blank" >http://dx.doi.org/10.7754/Clin.Lab.2016.160328</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.7754/Clin.Lab.2016.160328" target="_blank" >10.7754/Clin.Lab.2016.160328</a>
Alternative languages
Result language
angličtina
Original language name
Stability of Non-Activated Rotational Thromboelastometry Assay in Time of Citrated Blood (Appropriate Time Interval for Analysis)
Original language description
Background: Activated methods of thromboelastometry such as EXTEM and INTEM are routinely used in management of severe bleeding. However, sometimes the patient is bleeding despite the normal values of EXTEM/INTEM. Non-activated thromboelastometry (NATEM) is the most sensitive to coagulopathy and shows pathologic results in such cases. However, it is necessary to find an appropriate time interval between blood sampling and NATEM analysis as the results are strongly influenced by time. Methods: In 18 healthy volunteers we performed NATEM analyses of citrated blood samples at 0, 5, 10, 15, 20, 30, and 60 minutes after sampling. Results: All NATEM parameters showed a procoagulation trend with the time elapsing from blood sample collection with coagulation time (CT) being the most sensitive parameter. After 20 minutes this parameter became relatively stable as the difference among CT at 20th, 30th, and 60th minute was not statistically significant (p > 0.05). The least differences of CT values with maximum time window were found between 30 and 60 minutes. Conclusions: Citrated blood sample becomes stable after 20 minutes of storage but the time window between 30 and 60 minutes seems to be more suitable for NATEM analysis in clinical practice.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Laboratory
ISSN
1433-6510
e-ISSN
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Volume of the periodical
62
Issue of the periodical within the volume
11
Country of publishing house
DE - GERMANY
Number of pages
4
Pages from-to
2145-2148
UT code for WoS article
000387734600009
EID of the result in the Scopus database
2-s2.0-85009084347