Seasonality at the clinical onset of type 1 diabetes-Lessons from the SWEET database
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10332670" target="_blank" >RIV/00064203:_____/16:10332670 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/16:10332670
Result on the web
<a href="http://dx.doi.org/10.1111/pedi.12433" target="_blank" >http://dx.doi.org/10.1111/pedi.12433</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/pedi.12433" target="_blank" >10.1111/pedi.12433</a>
Alternative languages
Result language
angličtina
Original language name
Seasonality at the clinical onset of type 1 diabetes-Lessons from the SWEET database
Original language description
Background: Seasonality at the clinical onset of type 1 diabetes (T1D) has been suggested by different studies, however, the results are conflicting. This study aimed to evaluate the presence of seasonality at clinical onset of T1D based on the SWEET database comprising data from 32 different countries. Methods: The study cohort included 23 603 patients (52% males) recorded in the international multicenter SWEET database (48 centers), with T1D onset <= 20 years, year of onset between 1980 and 2015, gender, year and month of birth and T1D-diagnosis documented. Data were stratified according to four age groups (<5, 5-<10, 10-<15, 15-20 years) at T1D onset, the latitude of European center (Northern >= 50 degrees N and Southern Europe <50 degrees N) and the year of onset <= or >2009. Results: Analysis by month revealed significant seasonality with January being the month with the highest and June with the lowest percentage of incident cases (P < .001). Winter, early spring and late autumn months had higher percentage of incident cases compared with late spring and summer months. Stratification by age showed similar seasonality patterns in all four age groups (P <= .003 each), but not in children < 24 months of age. There was no gender or latitude effect on seasonality pattern, however, the pattern differed by the year of onset (P < .001). Seasonality of diagnosis conformed to a sinusoidal model for all cases, females and males, age groups, northern and southern European countries. Conclusions: Seasonality at T1D clinical onset is documented by the large SWEET database with no gender or latitude (Europe only) effect except from the year of manifestation.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pediatric Diabetes
ISSN
1399-543X
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
Supplement 23
Country of publishing house
DK - DENMARK
Number of pages
6
Pages from-to
32-37
UT code for WoS article
000389153800005
EID of the result in the Scopus database
2-s2.0-84992371576