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Total and high molecular weight adiponectin levels and prediction of insulin resistance

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F14%3A%230000737" target="_blank" >RIV/00098892:_____/14:#0000737 - isvavai.cz</a>

  • Alternative codes found

    RIV/00843989:_____/14:E0105269

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Total and high molecular weight adiponectin levels and prediction of insulin resistance

  • Original language description

    Adiponectin is a key component in the interrelationship between adiposity, insulin resistance and inflammation. Concentrations of adiponectin and its high molecular oligomer have been extensively evaluated as epidemiological markers of the risk for developing insulin resistance, type 2 diabetes mellitus or metabolic syndrome. The study analyzed levels of total adiponectin and its high molecular oligomer (HMW form) in a group of 269 metabolically healthy adults and in 300 patients with type 2 diabetes mellitus. In healthy individuals, both total and HMW adiponectin levels were significantly higher than in diabetic patients. Total and HMW adiponectin levels were adequately correlated with the Homeostatic Model Assessment of Insulin Resistance index. Logistic regression analysis showed that increased levels of both total adiponectin (OR 0.598; 95% CI 0.483?0.723) and the HMW form (OR 0.360; 95% CI 0.242?0.511) are a protective factor against the development of insulin resistance. The resu

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FN - Epidemiology, infection diseases and clinical immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT11098" target="_blank" >NT11098: Epidemiological study of adipose tissue proteins importance in relation to insulin resistance</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Experimental and Clinical Cardiology

  • ISSN

    1205-6626

  • e-ISSN

  • Volume of the periodical

    20

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    CA - CANADA

  • Number of pages

    7

  • Pages from-to

    5618-5624

  • UT code for WoS article

  • EID of the result in the Scopus database