Cortical activity modulation by botulinum toxin type A in patients with post-stroke arm spasticity: Real and imagined hand movement
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F14%3A%230000767" target="_blank" >RIV/00098892:_____/14:#0000767 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/14:33151015 RIV/61989592:15120/14:33151015
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Cortical activity modulation by botulinum toxin type A in patients with post-stroke arm spasticity: Real and imagined hand movement
Original language description
BACKGROUND: Our aim was to use functional magnetic resonance imaging (fMRI) to compare brain activation changes due to botulinum toxin A (BoNT) application between two chronic stroke patient groups with different degree of weakness treated for upper limbspasticity.METHODS: Fourteen ischemic stroke patients with hand weakness and spasticity were studied. Spasticity was scored by modified Ashworth scale (MAS). FMRI was performed 3 times: before (W0) and 4 (W4) and 11weeks (W11) after BoNT application. Group A: 7 patients (2 males, 5 females; mean age 59.14years) with hand plegia, who imagined moving fingers. Group B: 7 age-matched patients (6 males, 1 female; mean age 59.57years) able to perform sequential finger movement.RESULTS: BoNT transiently lowered MAS in W4 in both groups. In group A, activation of the frontal premotor cortex dominated and persisted for all three fMRI sessions whereas the ipsilesional cerebellum and cortex bordering bilateral intraparietal sulcus activation chan
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/NT13575" target="_blank" >NT13575: Changes in cortical organization and activation in patients with post-stroke spasticity following botulinum toxin treatment: fMRI study</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of the Neurological Sciences
ISSN
0022-510X
e-ISSN
—
Volume of the periodical
346
Issue of the periodical within the volume
1-2
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
276-283
UT code for WoS article
—
EID of the result in the Scopus database
—