Differences in the Modulation of Cortical Activity in Patients Suffering from Upper Arm Spasticity Following Stroke and Treated with Botulinum Toxin A

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F13%3A%230000437" target="_blank" >RIV/00098892:_____/13:#0000437 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/13:33144109 RIV/61989592:15120/13:33144109
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Differences in the Modulation of Cortical Activity in Patients Suffering from Upper Arm Spasticity Following Stroke and Treated with Botulinum Toxin A
Original language description
Aim: The aim of our functional magnetic resonance (fMRI) study was to localize the changes of cerebral cortex activation in stroke patients suffering from upper limb spasticity and treated with botulinum toxin A (BoNT). Materials and methodology: 34 patients suffering from upper limb post-stroke spasticity were examined; 9 of these patients were grouped into two homogenous subgroups that allowed independent further analysis. Group A consisted of four patients (2 males, 2 females; aged 25.5 +/- 3.4 years, range 22-31 years) who suffered from hand plegia. Group B consisted of five patients (4 males, 1 female; aged 67.0 +/- 11.1 years, range 54-80) who were able to perform real finger movement. The change of arm spasticity was assessed by using the modified Ashworth scale (MAS). fMRI was performed during imaginary movement (group A) or real movement of the impaired hand (group B). fMRI sessions were performed before (WO) and four weeks (W4) after BoNT treatment. Group B underwent addition
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/NT13575" target="_blank" >NT13575: Changes in cortical organization and activation in patients with post-stroke spasticity following botulinum toxin treatment: fMRI study</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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