The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F14%3A%230000799" target="_blank" >RIV/00098892:_____/14:#0000799 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients
Original language description
Dyslipidemias are very important risk factors for onset of atherosclerosis. Serum fibroblast growth factor 21 (FGF 21) could be a new promising marker to determine the risk of atherosclerosis. However, there is limited informatik about the relationshipsof FGF 21 and atherosclerosis in recent literature the aim of this study was to evaluace relationships of serum FGF 21 levels to intima-media thickness (IMT), as a surrogate marker of subclinical atherosclerosis manifestation, in dyslipidemic patients. We examined 155 individuals dividend into 3 groups: dyslipidemic patients with or without metabolit syndrome (MetS+, MetS-) and control. We found significantly higher serum FGF 21 levels and IMT in MetS+ group than in MetS- group (p?0,05) as well as in control (p?0,05). In MetS- group and in all dyslipidemic patients (MetS- and MetS+), IMT correlated positively with serum FGF 21 (r=0,486, r=0,573, p?0,01 both). In MetS- group, IMT was independently associate with FGF 21 (P?0,01). We verif
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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