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The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33151999" target="_blank" >RIV/61989592:15110/14:33151999 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The relationship of serum fibroblast growth factor 21 levels to intima-media thickness in dyslipidemic patients

  • Original language description

    ?Dyslipidemias are very important risk factors for onset of atherosclerosis. Serum fibroblast growth factor 21 (FGF 21) could be a new promising marker to determine the risk of atherosclerosis. However, there is limited informatik about the relationshipsof FGF 21 and atherosclerosis in recent literature the aim of this study was to evaluace relationships of serum FGF 21 levels to intima-media thickness (IMT), as a surrogate marker of subclinical atherosclerosis manifestation, in dyslipidemic patients.We examined 155 individuals dividend into 3 groups: dyslipidemic patients with or without metabolit syndrome (MetS+, MetS-) and control. We found significantly higher serum FGF 21 levels and IMT in MetS+ group than in MetS- group (p?0,05) as well as in control (p?0,05). In MetS- group and in all dyslipidemic patients (MetS- and MetS+), IMT correlated positively with serum FGF 21 (r=0,486, r=0,573, p?0,01 both). In MetS- group, IMT was independently associate with FGF 21 (P?0,01). We veri

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů