Fibroblast growth factor 21 and endothelial/hemostatic markers in dyslipidemic subjects
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33151970" target="_blank" >RIV/61989592:15110/14:33151970 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Fibroblast growth factor 21 and endothelial/hemostatic markers in dyslipidemic subjects
Original language description
Fibroblast growth factor 21 (FGF 21) has been suggested as an independent factor for the protection of cardiovascular systém cells. We performed an anylasis to evaluate a possible association of FGF 21 levels with endothelial/hemostatik markers in asymptomati dyslipidemic individuals. We hypothesized that a potential protective actioncould be reflected in plasma elevationof FGF 21 in patients with adverse dyslipidemi phenotype. The study was conducted with asymptomatic patients (n=214), wubsequently divided into two groups (control group /CG/, n=66, 38 males, 28 females; dyslipidemic group /DLP/, n=148, 70 males, 78 females), according to apolipoprotein B (Apo B) and triglyceride levels. The plasma FGF 21 levels were measured by ELISA, while biochemical and endothelial/hemostatik markers were analysed by routine kit methods. In DLP (i.e. individuals with TG ? 1,5 mmol/l and/or apo B ? 1,2 g/l), plasma fibrinogen and FGF 21 levels were significantly higher (p { 0,01 and p { 0,001) compa
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů