Chromosome 6q deletion correlates with poor prognosis and low relative expression of FOXO3 in chronic lymphocytic leukemia patients

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F17%3AN0000140" target="_blank" >RIV/00098892:_____/17:N0000140 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/17:00067568 RIV/00669806:_____/17:10363732 RIV/00216224:14110/17:00095685 RIV/61989592:15110/17:73581117
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/epdf/10.1002/ajh.24852" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1002/ajh.24852</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ajh.24852" target="_blank" >10.1002/ajh.24852</a>

Result language
angličtina
Original language name
Chromosome 6q deletion correlates with poor prognosis and low relative expression of FOXO3 in chronic lymphocytic leukemia patients
Original language description
Detection of genetic changes has improved the current risk stratification in chronic lymphocytic leukemia (CLL). Among the known recurrent chromosomal abnormalities,6q deletion is less frequent and controversy surrounding its prognostic significance still remains. The study aimed at a genetic analysis of a group of CLL patients with chromosome 6q deletion for determination of its prognostic significance, extent, the minimal deleted region (MDR) using array comparative genomic hybridization (arrayCGH), and finally to dermine the relative expression of candidate genes located therein.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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