Role of echocardiography and cardiac biomarkers in prediction of in-hospital mortality and long-term risk of brain infarction in pulmonary embolism patients.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F18%3AN0000127" target="_blank" >RIV/00098892:_____/18:N0000127 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/18:00104656 RIV/61989592:15110/18:73592936

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0010865017300802?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0010865017300802?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crvasa.2017.04.003" target="_blank" >10.1016/j.crvasa.2017.04.003</a>

Result language

angličtina

Original language name

Role of echocardiography and cardiac biomarkers in prediction of in-hospital mortality and long-term risk of brain infarction in pulmonary embolism patients.

Original language description

The aim of the prospective study was to evaluate the ability of echocardiography and cardiac biomarkers to predict in-hospital mortality and the risk of brain infarction during a 12-month follow-up period (FUP) with anticoagulation in pulmonary embolism (PE) patients. Methods: Eighty-eight consecutive acute PE patients (39 men, mean age 63 years) were enrolled; 78 underwent baseline echocardiography and brain magnetic resonance imaging (MRI). After a 12-month FUP, 58 underwent brain MRI. In-hospital mortality and the rates of new ischemic brain lesions (IBL) on MRI with clinical ischemic stroke (IS) events were predicted based on echocardiography. Results: Our series involved 88 patients, of whom 11 (12.5 %) presented high-risk PE, 24 (27.3 %) intermediate-high risk PE, 19 (21.6 %) intermediate-low risk PE and 34 (38.6 %) patients had low risk PE. Nine patients (10.2 %) died during hospitalization including high-risk PE 6/9 (66.6 %) and intermediate-high-risk PE 3/24 (12.5 %)]. cTnT (ODDS ratio - OR= 4.3; 95 % confidence interval 0.59–31.3, P = 0.014), NT-proBNP (OR 14.2 1.5–133.4, P = 0.02) were predictors of in-hospital mortality. Seventeen patients (19.3 %) experienced IS (n = 8) or new IBL (n = 9). Conclusions: High blood troponin T, NT-proBNP, RV dilatation/systolic dysfunction and pulmonary hypertension predicted in-hospital mortality. PFO/RLS presence and ST were predictors of clinically apparent/silent brain infarction

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cor et Vasa

ISSN

0010-8650

e-ISSN

1803-7712

Volume of the periodical

60

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

9

Pages from-to

e105-e113

UT code for WoS article

000429583200001

EID of the result in the Scopus database

2-s2.0-85019889981