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The Role of Tumor Microenvironment and Immune Response in Colorectal Cancer Development and Prognosis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F22%3A10157511" target="_blank" >RIV/00098892:_____/22:10157511 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15110/22:73615808

  • Result on the web

    <a href="https://www.por-journal.com/articles/10.3389/pore.2022.1610502/full" target="_blank" >https://www.por-journal.com/articles/10.3389/pore.2022.1610502/full</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3389/pore.2022.1610502" target="_blank" >10.3389/pore.2022.1610502</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Role of Tumor Microenvironment and Immune Response in Colorectal Cancer Development and Prognosis

  • Original language description

    Colorectal cancer (CRC) is one of the most common cancers worldwide. The patient&apos;s prognosis largely depends on the tumor stage at diagnosis. The pathological TNM Classification of Malignant Tumors (pTNM) staging of surgically resected cancers represents the main prognostic factor and guidance for decision-making in CRC patients. However, this approach alone is insufficient as a prognostic predictor because clinical outcomes in patients at the same histological tumor stage can still differ. Recently, significant progress in the treatment of CRC has been made due to improvements in both chemotherapy and surgical management. Immunotherapy-based approaches are one of the most rapidly developing areas of tumor therapy. This review summarizes the current knowledge about the tumor microenvironment (TME), immune response and its interactions with CRC development, immunotherapy and prognosis.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

    <a href="/en/project/NU21-03-00372" target="_blank" >NU21-03-00372: Small binding proteins targeting PD-1/PD-L1 immune checkpoint proteins as new diagnostic tools</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    PATHOLOGY &amp; ONCOLOGY RESEARCH

  • ISSN

    1219-4956

  • e-ISSN

    1532-2807

  • Volume of the periodical

    28

  • Issue of the periodical within the volume

    July

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    12

  • Pages from-to

    1610502

  • UT code for WoS article

    000872915300001

  • EID of the result in the Scopus database

    2-s2.0-85135522745