The role of tumor microenvironment and immune response in colorectal cancer development and prognosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F22%3AE0109659" target="_blank" >RIV/00843989:_____/22:E0109659 - isvavai.cz</a>
Result on the web
<a href="https://www.por-journal.com/articles/10.3389/pore.2022.1610502/full" target="_blank" >https://www.por-journal.com/articles/10.3389/pore.2022.1610502/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/pore.2022.1610502" target="_blank" >10.3389/pore.2022.1610502</a>
Alternative languages
Result language
angličtina
Original language name
The role of tumor microenvironment and immune response in colorectal cancer development and prognosis
Original language description
Colorectal cancer (CRC) is one of the most common cancers worldwide. The patient’s prognosis largely depends on the tumor stage at diagnosis. The pathological TNM Classification of Malignant Tumors (pTNM) staging of surgically resected cancers represents the main prognostic factor and guidance for decision-making in CRC patients. However, this approach alone is insufficient as a prognostic predictor because clinical outcomes in patients at the same histological tumor stage can still differ. Recently, significant progress in the treatment of CRC has been made due to improvements in both chemotherapy and surgical management. Immunotherapy-based approaches are one of the most rapidly developing areas of tumor therapy. This review summarizes the current knowledge about the tumor microenvironment (TME), immune response and its interactions with CRC development, immunotherapy and prognosis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pathology & oncology research
ISSN
1532-2807
e-ISSN
1532-2807
Volume of the periodical
28
Issue of the periodical within the volume
article 1610502
Country of publishing house
CH - SWITZERLAND
Number of pages
12
Pages from-to
1-12
UT code for WoS article
000872915300001
EID of the result in the Scopus database
2-s2.0-85135522745