Raman spectroscopy in the diagnosis of malignant biliary stricture: A feasibility study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F25%3A10158889" target="_blank" >RIV/00098892:_____/25:10158889 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1499387224001589?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1499387224001589?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.hbpd.2024.11.003" target="_blank" >10.1016/j.hbpd.2024.11.003</a>

Result language
angličtina
Original language name
Raman spectroscopy in the diagnosis of malignant biliary stricture: A feasibility study
Original language description
Biliary strictures are caused by both benign and malignant pathologies. Although up to 30% of biliary strictures are identified as benign, the vast majority are malignant with two major malignancies, namely pancreatic adenocarcinoma and cholangiocarcinoma (CC). Accurate diagnosis and precise localization play a vital role in the prognosis and management of the disease. In this study we primarily focused on the diagnosis of CC. The highest incidence of CC is in northeastern Thailand, where the incidence is found to be 100/100 000 in males and 50/100 000 in females. In Western countries, it is approximately (0.5–2.0)/100 000 individuals. CC is most often diagnosed between the ages of 70 and 80 years. The prognosis of biliary malignancies is dismal with overall five-year survival as low as 10%. We developed a new method that can provide real-time Raman measurements of biliary stricture and physiological bile duct tissue during an ERCP procedure. The method is based on the utilization of a portable Raman system equipped with a fiber-optic probe. Then the resulting raw data are subjected to spectral processing and statistical evaluation, including a cluster analysis.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30219 - Gastroenterology and hepatology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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