Exercise End-Tidal Carbon Dioxide Predicts Central Sleep Apnea in Heart Failure Patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00062593" target="_blank" >RIV/00159816:_____/15:00062593 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1378/chest.14-2114" target="_blank" >http://dx.doi.org/10.1378/chest.14-2114</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1378/chest.14-2114" target="_blank" >10.1378/chest.14-2114</a>

Result language

angličtina

Original language name

Exercise End-Tidal Carbon Dioxide Predicts Central Sleep Apnea in Heart Failure Patients

Original language description

Increased carbon dioxide (CO2) chemosensitivity and augmented exercise ventilation are characteristic of heart failure (HF) patients with central sleep apnea (CSA). The aim of this study was to test the hypothesis that decreased end-tidal CO2 by cardiopulmonary exercise testing predicts CSA in HF patients. METHODS: Consecutive ambulatory NYHA II-III HF patients were prospectively evaluated by CO2 chemosensitivity by rebreathe, cardiopulmonary exercise testing and polysomnography (PSG). Subjects were classified as either CSA (n=20) or no sleep apnea (n=13) by PSG; a central apnea-hypopnea index GREATER-THAN OR EQUAL TO5 defined CSA. Subgroups were compared by t-test or Mann Whitney test and data summarized as mean +- SD; p<0.05 was considered significant. RESULTS: At rest, subjects with CSA had higher CO2 chemosensitivity (INCREMENT V.E/INCREMENT PETCO2) (2.3+-1.0 vs. 1.6+-0.4L/min/mmHg; p=0.02), minute ventilation (V.E) (15+-7 vs. 10+-3L/min; p=0.02) and lower end-tidal CO2 (PETCO2) (3

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chest

ISSN

0012-3692

e-ISSN

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Volume of the periodical

147

Issue of the periodical within the volume

6

Country of publishing house

US - UNITED STATES

Number of pages

12

Pages from-to

1566-1573

UT code for WoS article

000355837900037

EID of the result in the Scopus database

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